Cross references: Cholesterol Cholesterol Synthesis
Coenzyme A - Wikipedia
"Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it (or a thioester, such as acetyl-CoA) as a substrate. "
In all living organisms, Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, from pantothenate and cysteine:
ATP + dephospho-CoA ADP + CoA
Enzyme nomenclature abbreviations in parentheses represent eukaryotic
and prokaryotic enzymes respectively. In some plants and bacteria,
including Escherichia coli, pantothenate can be synthesised de novo and is therefore not considered essential.
Thiol - Wikipedia
Thioester - Wikipedia