Human Neurotransmitters


Neurotransmitter (Wiki) 
http://en.wikipedia.org/wiki/Neurotransmitter  
Discusses 42 neurotransmitters.   


Glutamic Acid (Wiki) 
http://en.wikipedia.org/wiki/Glutamic_acid 
"The carboxylate anions and salts of glutamic acid are known as glutamates."  "Glutamate is a key molecule in cellular metabolism."  "Glutamate is the most abundant excitatory neurotransmitter in the vertebrate nervous system."  "Glutamate also serves as the precursor for the synthesis of the inhibitory GABA in GABA-ergic neurons."  "Glutamate does not easily pass the blood brain barrier, but instead this transport is mediated by a high affinity transport system.[14] It can also be converted into glutamine.

03-31-13 

I'm currently working on 
Dictionary of neuroanatomical terms for the Subcortical Brain .  My focus at the moment is neural architecture, but I occasionally run into a reference that says interesting things about neurotransmitters.  I'll list the links below with the expectation that I'll be coming back to them later.       


Nucleus Accumbens Septi
   


Pineal Gland   

Ventral Tegmental Area   



2006       
Tonic GABA(A) receptor-mediated currents in human brain 
http://www.ncbi.nlm.nih.gov/pubmed/16930441  
    "
GABA(A) receptors can mediate both phasic (synaptic) and tonic (extrasynaptic) forms of inhibition. It has been proposed that tonic inhibition plays a critical part in controlling neuronal and network excitability. Although tonic GABA(A) receptor-mediated currents have been well characterized in rodents, their existence in human tissue has yet to be demonstrated. Here we show that tonic currents can be recorded from human tissue obtained from patients undergoing temporal lobectomies. Tonic GABA(A) receptor-mediated currents were present in pyramidal cells and interneurons in layer V-VI of temporal neocortex and granule cells in the dentate gyrus. These tonic currents have cell type-specific pharmacologies, opening up the possibility of targeted therapeutics."     
 




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